Jose Serrano-Moreno , PhD
- Pedagogical : Currently I am dedicated to develop active learning environments in classroom and teaching labs to enhance critical thinking and independent performance in science students.
- Advising and Curriculum evaluation: I actively participate in curriculum development, content examination and student advising at Department, College and University levels
- Research: Biophysical characterization of membrane transport mechanisms: Functional analysis of membrane ion channels constituted by connexins and pannexins proteins
Educational & Professional Experience
Case Western Reserve University 2001 Ph.D. Cellular Physiology
Universidad Central de Venezuela 1989 Licenciado in Biology (Cell Biology)
Department of Biology, Western Washington University
Fellow of Cystic Fibrosis Foundation 2001-2007
Oregon Health & Science University School of Medicine
Department of Physiology and Pharmacology
Research Assistant 1990-1994
Instituto Venezolano de Investigaciones Cientificas (IVIC)
- Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC.(2009) Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore Biochemistry. 48(42):10078-88.
- Serrano, JR, Liu, X., Borg, E.R, Alexander, C.S, Shaw III, C.F and Dawson, DC (2006) CFTR: Ligand Exchange between a Permeant Anion ([Au(CN)2]–) and an Engineered Cysteine (T338C) Blocks the Pore. Biophys. J. 91: 1737-1748
- Liu, X, Alexander, C, Serrano, J, Borg, E and Dawson, DC (2006) Variable Reactivity of an Engineered Cysteine at Position 338 in Cystic Fibrosis Transmembrane Conductance Regulator Reflects Different Chemical States of the Thiol. J Biol Chem. 281(12):8275-85.