Jose Serrano-Moreno , PhD
Senior Instructor
Office
Location
BI161
Hours
Tentative office hours Spring 2021 : MWF 12:50 -1:30 or by appointment
Research Interests
- Pedagogical : Currently I am dedicated to develop active learning environments in classroom and teaching labs to enhance critical thinking and independent performance in science students.
- Advising and Curriculum evaluation: I actively participate in curriculum development, content examination and student advising at Department, College and University levels
- Research: Biophysical characterization of membrane transport mechanisms: Functional analysis of membrane ion channels constituted by connexins and pannexins proteins
Educational & Professional Experience
Case Western Reserve University 2001 Ph.D. Cellular Physiology
Universidad Central de Venezuela 1989 Licenciado in Biology (Cell Biology)
Professional Experience
Faculty 2007-
Department of Biology, Western Washington University
Postdoctoral experience:
Fellow of Cystic Fibrosis Foundation 2001-2007
Oregon Health & Science University School of Medicine
Department of Physiology and Pharmacology
Research Assistant 1990-1994
Instituto Venezolano de Investigaciones Cientificas (IVIC)
Recent Publications
- Alexander C, Ivetac A, Liu X, Norimatsu Y, Serrano JR, Landstrom A, Sansom M, Dawson DC.(2009) Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore Biochemistry. 48(42):10078-88.
- Serrano, JR, Liu, X., Borg, E.R, Alexander, C.S, Shaw III, C.F and Dawson, DC (2006) CFTR: Ligand Exchange between a Permeant Anion ([Au(CN)2]–) and an Engineered Cysteine (T338C) Blocks the Pore. Biophys. J. 91: 1737-1748
- Liu, X, Alexander, C, Serrano, J, Borg, E and Dawson, DC (2006) Variable Reactivity of an Engineered Cysteine at Position 338 in Cystic Fibrosis Transmembrane Conductance Regulator Reflects Different Chemical States of the Thiol. J Biol Chem. 281(12):8275-85.